Nano-Particulate Gene Carrier

Nano-Particulate Gene Carrier

Tech ID


Patent Status


Design Status


Technical Description

The present invention relates to the HMG CoA reductase gene encapsulated inorganic metallic nanoparticle and its application in plant biotransformation. More particularly, invention relates to calcium phosphate nanoparticle preparation actively conjugated/encapsulated with HMG Co-A reductase genes and its application in plant biotransformation process.

The invention further relates to a process of entrapping genetic material in nanoparticles of calcium phosphate of size below100nm diameter to form non-viral carrier which can be used suitably for the delivery of genes in the plant of Cichorium intybus L. The invention provides for the use of micellar solubilisation technique as a method of synthesis of HMG CoA reductase gene encapsulated calcium phosphate nanoparticle. The proposed method of biotransformation process in plant Cichorium intybus L. mediated by calcium phosphate nanoparticle encapsulated with HMG CoA reductase gene results in the biosynthesis enhancement of secondary plant metabolite.


The invention provides an improved method of gene transfer in plants that increases the gene transformation rate up to 30% and survival of transformed C. intybusupto50%


Plant Biotechnology




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Stage of Developments

Current Market

The global genome editing market is expected to reach $3,514.08 Million by 2019 from $1,845.25 Million in 2014, growing at a CAGR of 13.75%. Increased R&D expenditure and growth of biotechnology and pharmaceutical industries, increased funding for genomics research, and technological advancements are the primary growth drivers for this market during the forecast period (2014–2019). Moreover, increasing demand for synthetic genes, and global rise in production of genetically modified crops are also expected to drive market growth. However, stringent regulatory policies and adverse public perception related to genetic research may hinder the growth of this market.

The global genome editing market is segmented on the basis of applications, technologies and end users. On the basis of applications, the market is segmented into cell line engineering, animal genetic engineering, plant genetic engineering, and other applications. Of these, the cell line engineering segment accounted for the largest share of the global genome editing market in 2014. On the other hand, the animal genetic engineering segment is expected to grow at the highest growth rate during the forecast period.

Therefore, in view of the above market analysis, the present invention offers a high potential of commercialization.

Contact Person

Ms. Shruti Kaushik

IP Bazzaar Technology Pvt. Ltd.

IP Bazzaar Technology Pvt. Ltd.

12 First Floor, National Park, Lajpat Nagar-IV,
New Delhi-110024, India
Tel: [+91] 11-26360036;
Fax: [+91] 11-26360037;
Mobile: [+91]9810338816;