Technical Description
A novel inorganic Nanocarrier protecting plasmid vectors from external environments and efficiently delivering them into abnormal mammalian cells i.e. cancerous cell to induce apoptosis.
Problems Addressed
- Ineffective Toxic Cancer Treatments
- DNA Digestion by DNase
- Compromised Cellular Uptake
- Ineffective Plasmid Transport
- Low Transfection Rate
- Immunogenicity & Gene Recombination Possibility
- Plasma Membrane Electrostatic Repulsive Barrier for DNA uptake
Tech Features
- Inorganic Nanocarrier
- DNase Activity Protection
- Thermal Damage Protection
- Efficient Plasmid Transport in Cell
- High Transfection Rate
- p53 Mediated Apoptosis of Cancer Cells
- pH controlled DNA unloading
- Enhanced DNA Recovery
- Excellent Cellular Uptake by Cancer Cells
Target Audience
- Pharmaceutical Industry
- Diagnostic Centres
- Cancer Hospitals
- Oncology Research Centres
- Biomedical Device Industry
Tech ID: P27-1080 TRL 5 Patent Status: Granted Available For Exclusive and Non-exclusive License
