Nanocarrier Based Targeted Genetic Material Delivery
Tech ID
P27-1080
Patent Status
Patent Granted in India
Design Status
--
Technical Description
A novel inorganic Nanocarrier protecting plasmid vectors from external environments and efficiently delivering them into abnormal mammalian cells i.e. cancerous cell to induce apoptosis.
Problems Addressed
- Ineffective Toxic Cancer Treatments
- DNA Digestion by DNase
- Compromised Cellular Uptake
- Ineffective Plasmid Transport
- Low Transfection Rate
- Immunogenicity & Gene Recombination Possibility
- Plasma Membrane Electrostatic Repulsive Barrier for DNA uptake
TARGET AUDIENCE
- Pharmaceutical Industry
- Diagnostic Centres
- Cancer Hospitals
- Oncology Research Centres
- Biomedical Device Industry
TECH FEATURES
- Inorganic Nanocarrier
- DNase Activity Protection
- Thermal Damage Protection
- Efficient Plasmid Transport in Cell
- High Transfection Rate
- p53 Mediated Apoptosis of Cancer Cells
- pH controlled DNA unloading
- Enhanced DNA Recovery
- Excellent Cellular Uptake by Cancer Cells
P27-1080
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Available For
Exclusive and Non-exclusive License.
Cost
—
Stage of Developments
Technology Validated
Contact Person
Mr. Lalit Ambastha
IP Bazzaar Technology Pvt. Ltd.
IP Bazzaar Technology Pvt. Ltd.
12 First Floor, National Park, Lajpat Nagar-IV,
New Delhi-110024, India
Tel: [+91] 11-26360036;
Fax: [+91] 11-26360037;
Mobile: [+91]9811367838;
Email: tech@ipbazzaar.com;
www.ipbazzaar.com
New Delhi-110024, India
Tel: [+91] 11-26360036;
Fax: [+91] 11-26360037;
Mobile: [+91]9811367838;
Email: tech@ipbazzaar.com;
www.ipbazzaar.com