A Multifunctional Drug For Alzheimer
Tech ID
P27-1150
Patent Status
Granted in India
Design Status
--
Technical Description
The present invention provides a novel multifunctional molecule designed for the treatment of Alzheimer’s disease and other neurodegenerative diseases. The drug molecule is a 3-(4-hydroxy-3-methoxy-phenyl) prop2-enoic acid derivative that is coupled with heterocyclic or substituted aromatic amines.
Problems Addressed
- Gradual Memory Loss
- Symptomatic Relief Drugs / Short Term Relief
- Limited Efficacy of Existing Treatments
- Limited AChE Interaction
- Poor Solubility & Blood Brain Barrier Penetration
- Environmentally Unsafe
- Toxic Aβ1-42 Aggregation
- Ferulic Acid (FA) with Low LogP
- Poor Yield & Purification with Chromatography
- Oxidative Stress
TARGET AUDIENCE
- Pharmaceutical Industry
- Healthcare and Medical Sector
- Research and Development
TECH FEATURES
- Alleviate Symptoms & Reverse Neurodegeneration
- Combat FA Limitations
- High-Intensity Absorption at Neutral pH
- Improved AChE Inhibition in Low Micromolar Range with IC50
- High Yield without Chromatography Purification
- FA with Increased LogP
- Antioxidant Activity
- Inhibiting Mitochondrial Respiration
- Inhibition of Aβ1-42 Aggregation
- Improved Solubility and Blood Brain Barrier Penetration
P27-1150
Send download link to email.
Available For
Available for exclusive and non exclusive license
Sell off
Cost
—
Stage of Developments
Technology Validated
Contact Person
Mr. Lalit Ambastha
IP Bazzaar Technology Pvt. Ltd.
IP Bazzaar Technology Pvt. Ltd.
12 First Floor, National Park, Lajpat Nagar-IV,
New Delhi-110024, India
Tel: [+91] 11-26360036;
Fax: [+91] 11-26360037;
Mobile: [+91]9811367838;
Email: tech@ipbazzaar.com;
www.ipbazzaar.com
New Delhi-110024, India
Tel: [+91] 11-26360036;
Fax: [+91] 11-26360037;
Mobile: [+91]9811367838;
Email: tech@ipbazzaar.com;
www.ipbazzaar.com