Technical Description
The invention is a mild, bio-friendly method for synthesizing red luminescent, protein-protected silver nanoclusters using preformed phosphine-protected clusters as a precursor. Operating at a neutral pH without harsh reducing chemicals, the synthesis systematically internalizes noble metal cores into protein templates while fully preserving their structural integrity and native bioactivity.
Problems Addressed
- Low cell viability
- loss of their inherent bioactivity
- Unstable Silver Nanocluster Scarcity
- High-pH Strong Reductant Dependence
- Irreversible Protein Denaturation
- Rapid Nanodecomposition & Precipitation
Tech Features
- Preformed Silver TPP Cluster Precursor (pH 7.1)
- High Retention of Ag18 @BSA Bioactivity (89%)
- Biocompatible Cytosolic Internalization
- Slow Nucleation Mechanism
- High-Quantum-Yield Red Photoluminescence (25.1)
Target Audience
- Pharmaceutical & Biotechnology Industries
- Advanced Therapeutics & Targeted Medicine
- Specialty Chemical & Precursor Manufacturers
Tech ID: P06-2072 TRL 4 Patent Status: Granted Available For Exclusive and Non-exclusive License
