Technical Description The present invention relates to synthesis of novel sulfonamide derivatives of para amino benzoic acid as selective butrylcholinesterase (BuChE) inhibitors for the treatment of Alzheimer’s disease. Problems Addressed Undesirable Side Effects Limitations of Existing Treatments Tech Features Novel…
Technical Description The present invention relates to the use of rare earth doped HfO2 nanoparticles for rapid development of latent fingerprints (LFP). Problems Addressed Expensive Complicated Operation Hazardous to Environment Invisible Prints Challenges in Contrast & Sensitivity Tech Features Cost-Effective…
Technical Description The present invention relates to an multi-orifice nozzle nozzle assembly for uniformly delivering cryogenic fluid and increasing efficacy of cryospray process. Problems Addressed Expensive Non-uniform Spraying Tech Features Uniform Fluid Spray High Tissue Necrosis Multiple Fluid Application Reduction…
Technical Description The technology relates to a gold nanoparticle polymer composite. The composite is useful for space filler material applications, and biocompatible 3D scaffolds. Problems Addressed Time-Taking Process Use of Organic Solvent Complicated Procedure Limitations of Existing Techniques Tech Features…
Technical Description The technology relates to a ceramic foam utilizing red mud as industrial waste. It is highly porous with improved mechanical strength and can be shaped for various applications. Problems Addressed Expensive Complex Process Requires More Constituent Industrial Waste…
Technical Description The technology relates to a system for generation of traffic report for micro or meso-spatial area using data from crowdsource data, sensor, or both. Problems Addressed Low Accuracy No Traffic Report Generation No Traffic Related Parameters Generation Improper…
Technical Description The present invention provides a novel compound 2-(4-Bromophenyl)-5-(4-(pyridin-2-yl) 5 piperazin-1-yl)-1,3,4-oxadiazole which has multi-functional potential against Alzheimer’s disease. Problems Addressed Aβ Accumulation in Brain Limitations of Existing Treatments Poor Drug Efficacy No Multitargeted Molecules Tech Features Novel Compound Multitargeted…
Technical Description The present invention provides N-(1- benzylpiperidin-4-yl)-5-(4-(trifluoromethyl) phenyl)-1,3,4-oxadiazol-2-amine as a multitargeted ligand to treat neurodegenerative disease. Problems Addressed Aβ Accumulation in Brain Limitations of Existing Treatments Monofunctional Molecules Tech Features Novel Compound Multitargeted Ligand Inhibits Cholinesterases & BACE-1 No…
Technical Description The present invention provides a multifunctional compound 2-(2,4-difluorophenyl)-5-(4-(pyridin-2-yl) piperazin-1-yl)-1,3,4-oxadiazole, which has multi-functional potential for treating Alzheimer’s disease. Problems Addressed Aβ Accumulation in Brain Limitations of Existing Treatments Poor Drug Efficacy Tech Features High Bioavailability Inhibits Cholinesterases & BACE-1…
Technical Description The present invention provides a novel multifunctional hybrid molecule for the treatment of neurodegenerative diseases. It is a hybrid of N-benzylpiperidine and 5-(2,4-dichlorophenyl)-1,3,4-oxadiazole for the treatment of Alzheimer’s disease Problems Addressed Aβ Accumulation in Brain Decreased Cholinergic Activity…
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